소개

박정빈 교수는 2022년부터 부산대학교 Computational Omics 연구실을 이끌고 있습니다. 부산대학교에서 물리학 학사(2012), 서울대학교에서 물리학 석사(2014), 하이델베르크 대학교에서 생물학 박사(Dr. rer. nat., 2020) 학위를 취득했습니다.

논문(43)

• Universal conditional knockout approach to multiple species, from fish to human induced pluripotent stem cells

  Jung-Hwa Choi, Jihoon Moon, Youngchul Oh, Thomas M Klompstra, Yujin Kim, Gayoung Baek, Yejin Kwak, Yeongjun Kim, Sangmin Lee, Sujin Park, Jeongmin Ha, Ohbin Kwon, Young Ki Choi, Jeong Hun Kim, Ji-Hyun Lee, Jeongbin Park, Jong Kyoung Kim, Dong Ho Woo, Ki-Jun Yoon, Bon-Kyoung Koo, Heetak Lee

  Nucleic Acids Research 54(9):gkag480 · 2026

• Reproducible and shareable bioinformatics pipelines from natural-language prompts

  Hyeon-Min Kim, Hwayeon Jeong, Abyot Melkamu Mekonnen, Yeongjun Kim, Youngchul Oh, Heetak Lee, Cheulhee Jung, Jeongbin Park

  bioRxiv:2026.05. 28.719125 · 2026

• Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome

  Bokyong Kim#, So‐Hui Kim#, Jieun Kim, Eun‐Young Eo, Hyung‐Jun Kim, Jae Ho Lee, Choon‐Taek Lee, Taeho Kong, Su Kyoung Seo, Seunghee Lee, Jeongbin Park*, Young‐Jae Cho*

  Advanced Biology 10(1):e00225 · 2026

• Towards a transparent and reproducible AI-assisted research paper writing

  Jeongbin Park

  Genomics & Informatics 23(1):26 · 2025

• READRetro web: A user-friendly platform for predicting plant natural product biosynthesis

  Yejin Kwak, Taein Kim, Sang-Gyu Kim, Jeongbin Park

  Molecules and Cells 48(8):100235 · 2025

• From spots to cells: Cell segmentation in spatial transcriptomics with BOMS

  Ocima Kamboj, Jeongbin Park, Oliver Stegle, Fred A Hamprecht

  PloS one 20(6):e0311458 · 2025

• The mitochondrial genome data of the Capsicum annuum cv. Dempsey (Solanaceae)

  Seona Yun, Junseong Bae, Jeongbin Park, Hyeran Kim

  Data in Brief:111640 · 2025

• Variant-aware Cas-OFFinder: web-based in silico variant-aware potential off-target site identification for genome editing applications

  Abyot Melkamu Mekonnen#, Kang Seong#, Hyeran Kim, Jeongbin Park

  Nucleic Acids Research:gkaf389 · 2025

• RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response

  Teng-Feng Li, Paul Rothhaar, Arthur Lang, Oliver Grünvogel, Ombretta Colasanti, Santa Mariela Olivera Ugarte, Jannik Traut, Antonio Piras, Nelson Acosta-Rivero, Vladimir Gonçalves Magalhães, Emely Springer, Andreas Betz, Hao-En Huang, Jeongbin Park, Ruiyue Qiu, Gnimah Eva Gnouamozi, Ann-Kathrin Mehnert, Viet Loan Dao Thi, Stephan Urban, Martina Muckenthaler, Matthias Schlesner, Dirk Wohlleber, Marco Binder, Ralf Bartenschlager, Andreas Pichlmair, Volker Lohmann

  Frontiers in immunology 16:1568056 · 2025

• Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy

  Eun Young Jeon, Yejin Kwak, Hyeji Kang, Se Young Jin, Soojin Park, Ryeo Gyeong Kim, Dayoung Ko, Jae-Kyung Won, Anna Cho, Inkyung Jung, Chul-Hwan Lee, Jeongbin Park, Hyun-Young Kim, Jong-Hee Chae, Murim Choi

  Science Advances 11(11):eadr4443 · 2025

• Highly efficient CRISPR/Cas9-RNP mediated CaPAD1 editing in protoplasts of three pepper (Capsicum annuum L.) cultivars

  Hanyi Choi, Hyunjae Shin, Chan Yong Kim, Jeongbin Park, Hyeran Kim

  Plant Signaling & Behavior 19(1):2383822 · 2024

• READRetro: natural product biosynthesis predicting with retrieval‐augmented dual‐view retrosynthesis

  Taein Kim, Seul Lee, Yejin Kwak, Min‐Soo Choi, Jeongbin Park, Sung Ju Hwang, Sang‐Gyu Kim

  New Phytologist 243(6):2512-2527 · 2024

• Current computational methods for spatial transcriptomics in cancer biology

  Jaewoo Mo#, Junseong Bae#, Jahanzeb Saqib, Dohyun Hwang, Yunjung Jin, Beomsu Park, Jeongbin Park*, Junil Kim*

  Advances in Cancer Research 163:71-106 · 2024

• CWAS-Plus: estimating category-wide association of rare noncoding variation from whole-genome sequencing data with cell-type-specific functional data

  Yujin Kim, Minwoo Jeong, In Gyeong Koh, Chanhee Kim, Hyeji Lee, Jae Hyun Kim, Ronald Yurko, Il Bin Kim, Jeongbin Park, Donna M Werling, Stephan J Sanders, Joon-Yong An

  Briefings in Bioinformatics 25(4):bbae323 · 2024

• Reference-based cell type matching of in situ image-based spatial transcriptomics data on primary visual cortex of mouse brain

  Yun Zhang#, Jeremy A Miller#, Jeongbin Park#, Boudewijn P Lelieveldt, Brian Long, Tamim Abdelaal, Brian D Aevermann, Tommaso Biancalani, Charles Comiter, Oleh Dzyubachyk, Jeroen Eggermont, Christoffer Mattsson Langseth, Viktor Petukhov, Gabriele Scalia, Eeshit Dhaval Vaishnav, Yilin Zhao, Ed S Lein, Richard H Scheuermann

  Scientific Reports 13(1):9567 · 2023

• PyOncoPrint: a python package for plotting OncoPrints

  Jeongbin Park*, Nagarajan Paramasivam

  Genomics & Informatics 21(1):e14 · 2023

• GNU Data Language 1.0: a free/libre and open-source drop-in replacement for IDL/PV-WAVE

  Jeongbin Park, Gilles Duvert, Alain Coulais, Gregory V Jung, Sylwester Arabas, Brian Barker, Takeshi Enomoto, Sylvain Flinois, Oliver Gressel, Tomas Hillberg, Thibault Huillet, Jan Kohnert, Orion Poplawski, Eloi Rozier de Linage, Remi A Solås, Luke Stagner, Ole Streicher, James Tappin, Thierry Thomas, Jingwei Wang, Christian Wimmer

  Journal of Open Source Software 7(80):4633 · 2022

• Cell segmentation-free inference of cell types from in situ transcriptomics data

  Jeongbin Park#, Wonyl Choi#, Sebastian Tiesmeyer, Brian Long, Lars E Borm, Emma Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils, Naveed Ishaque

  Nature Communications 12:3545 · 2021

• Functional states in tumor-initiating cell differentiation in human colorectal cancer

  Martina K Zowada, Stephan M Tirier, Sebastian M Dieter, Teresa G Krieger, Ava Oberlack, Robert Lorenz Chua, Mario Huerta, Foo Wei Ten, Karin Laaber, Jeongbin Park, Katharina Jechow, Torsten Müller, Mathias Kalxdorf, Mark Kriegsmann, Katharina Kriegsmann, Friederike Herbst, Jeroen Krijgsveld, Martin Schneider, Roland Eils, Hanno Glimm, Christian Conrad, Claudia R Ball

  Cancers 13(5):1097 · 2021

• Transcriptional heterogeneity identifies functional states of tumor-initiating cell differentiation in human colorectal cancer

  Martina K Zowada, Stephan M Tirier, Sebastian M Dieter, Teresa Krieger, Ava Oberlack, Robert L Chua, Mario Huerta, Foo Wei Ten, Karin Laaber, Jeongbin Park, Katharina Jechow, Torsten Müller, Mathias Kalxdorf, Mark Kriegsmann, Katharina Kriegsmann, Friederike Herbst, Jeroen Krijgsveld, Martin Schneider, Roland Eils, Hanno Glimm, Christian Conrad, Claudia R Ball

  Cancer Research 80(16 Supplement):Abstract nr. 1491 · 2020

• Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

  Teresa G Krieger, Stephan M Tirier, Jeongbin Park, Katharina Jechow, Tanja Eisemann, Heike Peterziel, Peter Angel, Roland Eils, Christian Conrad

  Neuro-oncology:noaa091 · 2020

• ShinyButchR: Interactive NMF-based decomposition workflow of genome-scale datasets

  Andres Quintero, Daniel Hübschmann, Nils Kurzawa, Sebastian Steinhauser, Philipp Rentzsch, Stephen Krämer, Carolin Andresen, Jeongbin Park, Roland Eils, Matthias Schlesner, Carl Herrmann

  Biology Methods and Protocols 5(1):bpaa022 · 2020

• pheno-seq–linking visual features and gene expression in 3D cell culture systems

  Stephan M Tirier, Jeongbin Park, Friedrich Preußer, Lisa Amrhein, Zuguang Gu, Simon Steiger, Jan-Philipp Mallm, Teresa Krieger, Marcel Waschow, Björn Eismann, Marta Gut, Ivo G Gut, Karsten Rippe, Matthias Schlesner, Fabian Theis, Christiane Fuchs, Claudia R Ball, Hanno Glimm, Roland Eils, Christian Conrad

  Scientific Reports 9:12367 · 2019

• Web-based design and analysis tools for CRISPR base editing

  Gue-Ho Hwang#, Jeongbin Park#, Kayeong Lim, Sunghyun Kim, Jihyeon Yu, Eunchong Yu, Sang-Tae Kim, Roland Eils, Jin-Soo Kim, Sangsu Bae

  BMC Bioinformatics 19:542 · 2018

• IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas

  Rabea Wagener, Cristina López, Kortine Kleinheinz, Julia Bausinger, Sietse M Aukema, Inga Nagel, Umut H Toprak, Julian Seufert, Janine Altmüller, Holger Thiele, Christof Schneider, Julia Kolarova, Jeongbin Park, Daniel Hübschmann, Eva M Murga Penas, Hans G Drexler, Andishe Attarbaschi, Randi Hovland, Eigil Kjeldsen, Michael Kneba, Udo Kontny, Laurence De Leval, Peter Nürnberg, Ilske Oschlies, David Oscier, Brigitte Schlegelberger, Stephan Stilgenbauer, Wilhelm Wössmann, Matthias Schlesner, Birgit Burkhardt, Wolfram Klapper, Elaine S Jaffe, Ralf Küppers, Reiner Siebert

  Blood 132(21):2280-2285 · 2018

• IG-MYC-positive leukemia and lymphoma with precursor B-cell phenotype are genetically and epigenetically distinct from Burkitt lymphomas

  Cristina Lopez, Rabea Wagener, Kortine Kleinheinz, Julia Bausinger, Sietse M Aukema, Inga Nagel, Umut H Toprak, Julian Seufert, Janine Altmueller, Holger Thiele, Christof Schneider, Julia Kolarova, Jeongbin Park, Daniel Huebschmann, Eva M Murga Penas, Hans G Drexler, Andishe Attarbaschi, Randi Hovland, Eigil Kjeldsen, Michael Kneba, Udo Kontny, Laurence de Leval, Peter Nuernberg, Ilske Oschlies, David Oscier, Brigitte Schlegelberger, Stephan Stilgenbauer, Wilhelm Woessmann, Matthias Schlesner, Birgit Burkhardt, Wolfram Klapper, Elaine S Jaffe, Ralf Kueppers, Reiner Siebert

  British Journal of Haematology 182(S1):19-21, Abstract nr. 23 · 2018

• HTSlib-js: developer toolkit for a client-side JavaScript interface for HTSlib

  Jeongbin Park#, Liam H Childs#, Matthias Schlesner, Roland Eils

  bioRxiv:397935 · 2018

• Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo”

  Sang-Tae Kim#, Jeongbin Park#, Daesik Kim, Kyoungmi Kim, Sangsu Bae, Matthias Schlesner, Jin-Soo Kim

  Nature Methods 15(4):239-240 · 2018

• Cpf1-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cpf1

  Jeongbin Park, Sangsu Bae

  Bioinformatics 34(6):1077-1079 · 2018

• Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin

  Manuel Rodríguez-Paredes, Felix Bormann, Günter Raddatz, Julian Gutekunst, Carlota Lucena-Porcel, Florian Köhler, Elisabeth Wurzer, Katrin Schmidt, Stefan Gallinat, Horst Wenck, Joachim Röwert-Huber, Evgeniya Denisova, Lars Feuerbach, Jeongbin Park, Benedikt Brors, Esther Herpel, Ingo Nindl, Thomas G Hofmann, Marc Winnefeld, Frank Lyko

  Nature Communications 9:577 · 2018

• RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia

  Daniel B Lipka, Tania Witte, Reka Toth, Jing Yang, Manuel Wiesenfarth, Peter Nöllke, Alexandra Fischer, David Brocks, Zuguang Gu, Jeongbin Park, Brigitte Strahm, Marcin Wlodarski, Ayami Yoshimi, Rainer Claus, Michael Lübbert, Hauke Busch, Melanie Boerries, Mark Hartmann, Maximilian Schönung, Umut Kilik, Jens Langstein, Justyna A Wierzbinska, Caroline Pabst, Swati Garg, Albert Catalá, Barbara De Moerloose, Michael Dworzak, Henrik Hasle, Franco Locatelli, Riccardo Masetti, Markus Schmugge, Owen Smith, Jan Stary, Marek Ussowicz, Marry M Van Den Heuvel-Eibrink, Yassen Assenov, Matthias Schlesner, Charlotte Niemeyer, Christian Flotho, Christoph Plass

  Nature Communications 8:2126 · 2017

• Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations

  Julia Jabs, Franziska M Zickgraf, Jeongbin Park, Steve Wagner, Xiaoqi Jiang, Katharina Jechow, Kortine Kleinheinz, Umut H Toprak, Marc A Schneider, Michael Meister, Saskia Spaich, Marc Sütterlin, Matthias Schlesner, Andreas Trumpp, Martin Sprick, Roland Eils, Christian Conrad

  Molecular Systems Biology 13:955 · 2017

• Deciphering programs of transcriptional regulation by combined deconvolution of multiple omics layers

  Daniel Hüebschmann, Nils Kurzawa, Sebastian Steinhauser, Philipp Rentzsch, Stephen Krämer, Carolin Andresen, Jeongbin Park, Roland Eils, Matthias Schlesner, Carl Herrmann

  bioRxiv:199547 · 2017

• CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection

  Heon Seok Kim, Kyungjin Lee, Sangsu Bae, Jeongbin Park, Chong-Kyo Lee, Meehyein Kim, Eunji Kim, Minju Kim, Seokjoong Kim, Chonsaeng Kim, Jin-Soo Kim

  Journal of Biological Chemistry 292(25):10664-10671 · 2017

• Digenome-seq web tool for profiling CRISPR specificity

  Jeongbin Park, Liam Childs, Daesik Kim, Gue-Ho Hwang, Sunghyun Kim, Sang-Tae Kim, Jin-Soo Kim, Sangsu Bae

  Nature Methods 14(6):548-549 · 2017

• Cas-analyzer: an online tool for assessing genome editing results using NGS data

  Jeongbin Park, Kayeong Lim, Jin-Soo Kim, Sangsu Bae

  Bioinformatics 33(2):286-288 · 2017

• Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9

  Jeongbin Park, Jin-Soo Kim, Sangsu Bae

  Bioinformatics 32(13):2017-2023 · 2016

• Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

  Daesik Kim, Sojung Kim, Sunghyun Kim, Jeongbin Park, Jin-Soo Kim

  Genome Research 26(3):406-415 · 2016

• Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites

  Jeongbin Park, Sangsu Bae, Jin-Soo Kim

  Bioinformatics 31(24):4014-4016 · 2015

• Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

  Daesik Kim, Sangsu Bae, Jeongbin Park, Eunji Kim, Seokjoong Kim, Hye Ryeong Yu, Jinha Hwang, Jong-Il Kim, Jin-Soo Kim

  Nature Methods 12(3):237-243 · 2015

• Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

  Sangsu Bae#, Jeongbin Park#, Jin-Soo Kim

  Bioinformatics 30(10):1473-1475 · 2014

• Scaling GDL for multi-cores to process Planck HFI beams Monte Carlo on HPC

  Alain Coulais, Marc Schellens, Gilles Duvert, Jeongbin Park, Orion Poplawski, Sylwester Arabas, Stephane Erard, Benjamin Laurent, Mathieu Pinter, Nodar Kasradze, Mouadh Ayad

  Astronomical Data Analysis Software and Systems XXIII 485:331 · 2014

• Protein conformational dynamics dictate the binding affinity for a ligand

  Moon-Hyeong Seo, Jeongbin Park, Eunkyung Kim, Sungchul Hohng, Hak-Sung Kim

  Nature Communications 5:3724 · 2014