In KOBRA Reports 2026, we reported on a joint symposium sharing recent advances and research directions in single-cell and spatial omics in Korea.
Decoding Biology
Through Data & AI
We apply AI to large-scale biomedical data, turning complex datasets into biological and clinical insight.
Research Highlights
Single Cell & Spatial Omics
Mapping cell types in tissue and resolving cellular heterogeneity — from spatial transcriptomics to single-cell data.
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CRISPR Informatics
Widely-used web tools for CRISPR guide design and off-target analysis.
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AI & Machine Learning
Deep and probabilistic models for biology — and AI as a daily research tool.
Learn moreAbout Our Lab
The Computational Omics Laboratory at Pusan National University analyzes large-scale biomedical data using machine learning and probabilistic methods. We work across spatial omics, single-cell omics, and CRISPR informatics — and we use AI as a daily research tool — to turn complex datasets into biological and clinical insight.
Meet the teamNews
In this 2026 preprint co-authored by Sohui Kim and Yuhui Jeong, we present a human lung organoid-on-a-chip model that mimics SARS-CoV-2 infection at an air-liquid interface.
Read moreIn Cancer Research and Treatment: Official Journal of Korean Cancer Association in 2025, we examined how patients’ liver function before treatment is linked to patterns of liver toxicity after immune checkpoint inhibitor therapy, in a paper co-authored by Sohui Kim.
Read moreIn bioRxiv in 2026, we presented a way to create bioinformatics pipelines from natural-language prompts so they are easier to reproduce and share, led by Hyeonmin Kim and Abyot Melkamu Mekonnen.
Read moreRecent Publications
View all publicationsSingle Cell and Spatial Omics Korea (SCSOK)-Institute for Basic Science (IBS) Joint Symposium
Jeongbin Park, Junil Kim, Heetak Lee
KOBRA Reports 2(2):21
Recapitulating SARS-CoV-2 Infection in a Human Lung Organoid-on-a-Chip at the Air-Liquid Interface
Sohyun Park, So-Hui Kim, Bokyong Kim, Eun-Young Eo, Hyung-Jun Kim, Yuhui Jeong, Jeongbin Park, Young-Jae Cho
Characteristics of Immune Checkpoint Inhibitor–Related Hepatotoxicity Based on the Baseline Liver Function
Won-Jung Jung, Eun-Jung Jo, Ye-Jee Kim, Mihyun Park, Eunji Kim, Yu-Seon Jung, Sook Ryun Park, Ji Seon Oh, So-Hui Kim, Jeongbin Park, Sun-Young Jung, Nakyung Jeon
Cancer Research and Treatment: Official Journal of Korean Cancer Association 58(3):709
Reproducible and shareable bioinformatics pipelines from natural-language prompts
Hyeon-Min Kim, Hwayeon Jeong, Abyot Melkamu Mekonnen, Yeongjun Kim, Youngchul Oh, Heetak Lee, Cheulhee Jung, Jeongbin Park
bioRxiv:2026.05. 28.719125
Universal conditional knockout approach to multiple species, from fish to human induced pluripotent stem cells
Jung-Hwa Choi, Jihoon Moon, Youngchul Oh, Thomas M Klompstra, Yujin Kim, Gayoung Baek, Yejin Kwak, Yeongjun Kim, Sangmin Lee, Sujin Park, Jeongmin Ha, Ohbin Kwon, Young Ki Choi, Jeong Hun Kim, Ji-Hyun Lee, Jeongbin Park, Jong Kyoung Kim, Dong Ho Woo, Ki-Jun Yoon, Bon-Kyoung Koo, Heetak Lee
Nucleic Acids Research 54(9):gkag480
Correction: Towards a transparent and reproducible AI-assisted research paper writing
Jeongbin Park
Genomics & Informatics 24:7
Join our lab
Interested in biomedical informatics? We welcome self-motivated students from diverse backgrounds. Apply now.
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